BP MANAGER

Supplement Facts Serving Size 1 Tablet
	Amount Per Tablet
Proprietary Herbal Blend Stevia (Stevia rebaudiana)leaf extract, Olive (Olea europaea)leaf extract, Hawthorn (Crategus oxyacantha)leaf and flower extract, Dandelion (Taraxacum officinale)leaf, Lycopene	570 mg?
� Daily Values not established.

Why take BP Manager?
Because this proprietary herbal blend features five powerful, clinically-studied ingredients:*

• Stevia leaf extract supports healthy blood pressure levels?*
• Hawthorn extract balances sodium and fluid levels*
• Olive leaf extract supports blood pressure health*
• Dandelion leaf helps reduce fluid retention*
• Lycopene supports arteries, circulation and heart health*

See the results in 8-weeks:*
* Recent studies showed positive results when consumers used BP Manager daily over an 8-week period.� *
*Maintains healthy blood pressure levels already within normal range.

Recommendations
One tablet three times daily with meals.
Other Ingredients
cellulose, modified cellulose, modified cellulose gum, magnesium sterate, vegetable juice color, soy lecethin, and carnuba wax.
Contains no sugar, salt, yeast, wheat, gluten, corn,dairy products, artifical flavoring or perservatives. All colors used are from natural sources.

Technical Data
DESCRIPTION
BP Manager is a combination of clinically studied ingredients known for their support of healthy blood pressure already within normal limits.† The proprietary blend includes the herbs dandelion, stevia, olive leaf, and hawthorn in combination with lycopene, a potent antioxidant with proven support for heart health.†
BP Manager:

• • Scientifically-studied formula†1
• • Supports healthy blood pressure already within normal levels†
• • Exclusive, proprietary ingredient blend
• • Optimum benefits will be noted within 8 weeks†

HOW DOES IT WORK?

Blood pressure is defined as the flow of the blood from the heart, and the resistance that blood flow encounters in the arteries and vessels. Two values are used to determine blood pressure levels. Systolic pressure is measured during the contraction of the heart and ventricles. Diastole occurs between contractions when the heart rests and the heart cavities fill with blood. Diastolic pressure alternates rhythmically with systolic pressure.

The ingredients in BP Manager individually have a long history of traditional use, and have been shown in modern clinical studies to have significant benefits for heart health.† This proprietary blend was recently utilized in a scientific study in which 100% of participants experienced significant support for retention of healthy blood pressure levels already within normal limits.†1

BP Manager contains clinically-studied ingredients that support healthy systolic and diastolic blood pressure already within normal limits.† Research on other nutrients for the support of healthy blood pressure levels typically have found significant benefits only for the retention of healthy systolic blood pressure levels already within normal limits.† Support for diastolic was less consistently noted—until now.†1,2

Dandelion (Taraxacum officinale) Leaf Extract: Dandelion leaves are rich in vitamin A, and include amounts of vitamin C, vitamin D, various B vitamins, magnesium, potassium, and zinc among other nutrients. Dandelion has a long history of traditional use associated helping reduce fluid retention in the body.†3 Flavonoids isolated found in dandelions may be responsible for its beneficial effects.†3-6

Lycopene: is a member of the carotenoid family, related to beta-carotene. Research shows that lycopene is associated with greater free-radical scavenging ability than any other carotenoid.†7,8 Increased intake of lycopene has been associated with beneficial support of heart health in clinical studies, including a multi-center study.†9,10 Lycopene is also currently being studied for its association with immune system and prostate health.†11-13

Stevia (Stevia rebaudiana) leaf extract: the leaf of stevia is considered the beneficial part of the plant.† Extracts of stevia have been shown to support healthy vasodilation, arterial wall health and blood pressure already within normal limits.†14-16

Stevia may have other benefits that extend beyond support of healthy blood pressure. Clinical studies also associated stevia extract with support of healthy blood sugar already within normal limits in all participants.†17,18

Olive (Olea europaea) Leaf Extract: Olives and olive oil are major components of the Mediterranean diet. Olive leaf extract contains the beneficial compound oleuropein, which is associated with healthy vasodilation and arterial structure.†19-21

Hawthorn (Crataegus spp. oxycantha) extract: Hawthorn has been associated with support of the heart since ancient times. Modern research considers bioflavonoid complexes in hawthorn leaf and flower, including vitex-2-rhamnoside, responsible for the plant's beneficial effects.† Hawthorn extract is associated with healthy arterial blood flow, normal blood vessel dilation and healthy sodium balance already within normal limits.†22-29

Hawthorn also supports healthy cholesterol levels already within normal limits, possibly through antioxidant activity.†30-33 Like stevia extract, hawthorn also shows potential benefits supporting normal blood sugar levels already within healthy limits.†34

The following chart listing the benefits of each:

Ingredient	Benefit
Dandelion Leaf Extract	Dandelion leaves are rich in vitamin A and other nutrients. Dandelion leaf has been traditionally associated with support of healthy fluid balance in the body already within normal limits†3,5 Dandelion also helps reduce fluid retention in the body.†3,6
Lycopene	Lycopene is a member of the carotenoid family that shows great antioxidant activity†7-8 In clinical studies, lycopene was associated with support of cardiovascular health.†9,10 Lycopene is also currently being studied for its association with immune system and prostate health.†11
Stevia Extract	Shows support of healthy blood pressure already within normal limits, and is associated with normal arterial wall thinkness and support of healthy blood vessel dilation†14-16 Clinical studies also associated stevia extract with support of healthy blood sugar levels already within normal limits in all participants†17,18
Olive Leaf Extract	Olive leaf extract contains the beneficial compound oleuropein, which is assocaited with healthy vasorelaxation and arterial structure.†19-21
Hawthorn Extract	Traditionally used to support heart health.† Hawthorn contains procyanidins, which are associated with its beneficial effects for supporting heart health.†22-23,25

RECOMMENDATIONS One tablet three times daily with meals. PRECAUTIONS Monitor your blood pressure regularly. Consult your healthcare practitioner prior to use if your blood pressure is outside the normal range, if you are taking blood pressure lowering medication, or if you are pregnant or nursing. HOW IS IT SUPPLIED? • 90 Tablets

STORAGE RECOMMENDATIONS Store at controlled room temperature, 59° to 86°F (15°-30°C). REFERENCES

• 1. A pilot-study of the effectiveness and safety of an herbal blend in pre-hypertensive subjects. 2004. Unpublished.
• 2. Qidwai W, Qureshi R, Hasan SN, Azam SI. Effect of dietary garlic (Allium Sativum) on the blood pressure in humans--a pilot study. J Pak Med Assoc. 2000 Jun;50(6):204-7. PMID: 10979632
• 3. Kotilla-Racz E, Racz G, Solomon A. The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals. Planta Med. 1974 Nov;26(3):212-7.
• 4. Williams CA, Goldstone F, Greenham J. Flavonoids, cinnamic acids and coumarins from the different tissues and medicinal preparations of Taraxacum officinale. Phytochemistry. 1996 May;42(1):121-7. PMID: 8728061
• 5. Dandelion Herb. In: Herbal Medicine: Expanded Commission E Monographs. Blumenthal M, Goldberg A, Brinkmann J, eds. Integrative Medicine Communications. Newton, MA. 2000;79-80.
• 6. Taraxacum officinale. Monograph. Altern Med Rev. 1999 Apr;4(2):112-4. PMID: 10231611
• 7. Di Mascio P, Kaiser S, Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys. 1989 Nov 1;274(2):532-8. PMID: 2802626
• 8. Gianetti J, Pedrinelli R, Petrucci R, Lazzerini G, De Caterina M, Bellomo G, De Caterina R. Inverse association between carotid intima-media thickness and the antioxidant lycopene in atherosclerosis. Am Heart J. 2002 Mar;143(3):467-74. PMID: 11868053
• 9. Arab L, Steck S. Lycopene and cardiovascular disease. Am J Clin Nutr. 2000;71(suppl):1691S-5S.
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• 11. Agarwal S, Rao AV. Tomato lycopene and its role in human health and chronic diseases. CMAJ. 2000;163(6):739-744.
• 12. Gann P, Ma J, Giovannucci E, Willett W, Sacks FM, Henneckens CH, et al. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res. 1999;59:1225-30.
• 13. Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams AW, Moore BJ, Erdman JW Jr. cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers Prev. 1996 Oct;5(10):823-33. PMID: 8896894
• 14. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res. 1996 May;29(5):669-75. PMID: 9033821
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• 17. Jeppesen PB, Gregersen S, Rolfsen SE, Jepsen M, Colombo M, Agger A, Xiao J, Kruhoffer M, Orntoft T, Hermansen K. Antihyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki rat. Metabolism. 2003 Mar;52(3):372-8. PMID: 12647278
• 18. Curi R, Alvarez M, Bazotte RB, Botion LM, Godoy JL, Bracht A. Effect of stevia rebaudiana on glucose tolerance in normal adult humans. Braz J Med Biol Res. 1986;19(6):771-4. PMID: 3651629.
• 19. Carluccio MA, Siculella L, Ancora MA, Massaro M, Scoditti E, Storelli C, Visioli F, Distante A, De Caterina R. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):622-9. Epub 2003 Feb 20. PMID: 12615669
• 20. Massaro M, De Caterina R. Vasculoprotective effects of oleic acid: epidemiological background and direct vascular antiatherogenic properties. Nutr Metab Cardiovasc Dis. 2002 Feb;12(1):42-51. PMID: 12125230
• 21. Tuck KL, Hayball PJ. Major phenolic compounds in olive oil: metabolism and health effects. J Nutr Biochem. 2002 Nov;13(11):636-644. PMID: 12550060
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• 25. Kim SH, Kang KW, Kim KW, Kim ND. Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta. Life Sci. 2000;67(2):121-31. PMID: 10901280
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• 28. Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol. 1983 Apr 1;32(7):1141-8. PMID: 6342623
• 29. Uchida S, Ikari N, Ohta H, Niwa M, Nonaka G, Nishioka I, Ozaki M. Inhibitory effects of condensed tannins on angiotensin converting enzyme. Jpn J Pharmacol. 1987 Feb;43(2):242-6. PMID: 3033368
• 30. Shanthi S, Parasakthy K, Deepalakshmi PD, Devaraj SN. Hypolipidemic activity of tincture of Crataegus in rats. Indian J Biochem Biophys. 1994 Apr;31(2):143-6. PMID: 7927437
• 31. Zhang Z, Ho WK, Huang Y, James AE, Lam LW, Chen ZY. Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet. J Nutr. 2002 Jan;132(1):5-10. PMID: 11773500
• 32. Zhang Z, Chang Q, Zhu M, Huang Y, Ho WK, Chen Z. Characterization of antioxidants present in hawthorn fruits. J Nutr Biochem. 2001 Mar;12(3):144-152. PMID: 11257463
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• 34. Jouad H, Lemhadri A, Maghrani M, Burcelin R, Eddouks M. Hawthorn evokes a potent anti-hyperglycemic capacity in streptozotocin-induced diabetic rats. Herb Pharmcother. 2003;3(2):19-29.